Sarah Denny

Company: Scribe Therapeutics

Job title: Director, Molecular Engineering

Seminars:

Comprehensive Engineering of CasX Holoenzyme to Create an X-Editing Toolbox with High Activity, Specificity, & Targetability 12:00 pm

Comprehensive and holistic engineering to increase CasX stability, DNA-binding ability, and cleavage activity to create the X-editing platform XE is far more active than wild-type CasX, and edits more effectively than small Cas9 variants and other engineered small Cas12 variants Further modifications for PAM preferences, enabling wider range of targeting and precise specificityRead more

day: Day 1 Track A AM