Jungjoon Lee

Company: ToolGen

Job title: Research Head, Platform Development Team,

Bio:

Dr. Jungjoon K. Lee holds a Ph.D. from Stanford University and a BA/MSci from the University of Cambridge. He serves as the research head for Toolgen’s platform development team, where he has been involved in the development of ground-breaking tools, including TAPE-seq (Nature Communications 2022), Extru-seq (Genome Biology 2023), Sniper-Cas9 (Nature Communications 2018), and Sniper2L (Nature Chemical Biology 2023).

Seminars:

Panel Discussion: Defining Thresholds & Cut-Off Values for Off-Target Analysis 4:45 pm

Developing a framework for setting acceptable levels of off-target mutagenesis Understanding the influence of individual genetic variance and how this may affect off-target editing levels How can industry ensure patient risk-benefit attitudes are taken into account? What actually are the functional consequences of observed off-targets?Read more

day: Day 1 PM

Overcoming the Trade-Off Between Specificity and Activity 11:15 am

Outlining Sniper2L, a high-fidelity Cas variant with retained high activity and specificity Exploring screening methods used in its generation Comparing activity and specificity levels of Sniper2L with other Cas 9 variantsRead more

day: Day 2 Track A AM