Mitigation of Chromosome Loss in Clinical CRISPRCas9-Engineered

Time: 11:15 am
day: Day 2 Track B AM

Details:

• Cas9 genome editing results in partial and whole chromosome loss at target sites across the genome
• Cas9-induced chromosome loss in primary human T cells persists in ex vivo culture for weeks
• A modification in clinical genome editing protocol dramatically reduces the rate of Cas9-induced chromosome loss in T cells

Speakers:

Connor Tsuchida Dr. Connor Tsuchida completed his PhD in Bioengineering from UC Berkeley and UC San Francisco as a NIH F31 fellow, working in the laboratory of Read more