Enabling Rapid Discovery and Development of Next- Generation Genome Editing Tools Through Metagenomics
Time: 1:15 pm
day: Day 2 Track A PM
Details:
- Metagenomics enables rapid development of compact systems for in vivo therapeutic genome editing
- These systems are capable of editing the genome through double strand breaks, base editing, prime editing, and targeted transgene integration
- Novel CRISPR-associated transposases are capable of programmable and site-specific integration of large DNA cargoes into the genome of human cells
- Next-generation genome editing tools unlock rapid therapeutic translation