Paul Donohoue

Paul Donohoue

Company: Caribou Biosciences

Job title: Senior Scientist – Platform Discovery Group Lead

Seminars:

Utilising Hybrid Guide Methods to Refine Genome Editing Precision 2:30 pm

Understanding how CRISPR hybrid DNA-RNA (chRDNA) guides function to increase gene editing specificity and reduce levels of off-target editing compared to traditional all-RNA systems Demonstration of the activity of chRDNA guides across both the Cas9 and Cas12a CRISPR systems Optimization of nuclear delivery to increase editing efficiency in T cell and iPSCsRead more

day: Day One

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