Howard Wu

Howard Wu

Company: Full Circles Therapeutics

Job title: Founder & Chief Scientific Officer


Choosing the Right Donor DNA Format 4:00 pm

The use of double-stranded DNA (dsDNA) donors is associated with poor knock-in efficiency and increased cytotoxicity and potential insertional mutagenesis, which is driven by genomic integration of dsDNA through the HDR repair processes Understanding modified ssODN donors as an approach to enhance efficiency for knock-ins Assessing preliminary data from circular single-stranded DNA (cssDNA) and its…Read more

day: Day Two

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