Singling Out the Cuts: Single-Cell Multi-Modal Analysis for CRISPR- Edited Cells
Time: 11:35 am
day: Day Two
Details:
- Editing cells with CRISPR results in cell populations that have cell-to-cell variation in editing outcomes
- Currently, time-consuming clonal isolation and expansion is necessary to identify the editing profile of individual cells
- With the Tapestri Platform, it is possible to measure multiplex edits, zygosity, and off-target events across thousands of cells in a single assay
- This powerful technology holds much promise for modelling diseases like cancer, and to characterize cell and gene therapies